Galantamine vs Huperzine A? Which is more effective at immediately increasing ach receptor activity? What are the various pros and cons of each? Do they need to be stacked with choline precursors? If so, which choline precursors are the most potent by weight at increasing levels of choline and acetyl-choline?
Are there any other potent ACH releasers, CHAT inducers, or ACHE inhibitors that are effective at minus 250 mg doses? Preferably dietary or natural in origin.
I am also interested in Butyrylcholinesterase inhibitors of natural origin or of dietary supplement status.
I am looking for both personal anecdotal experiences and scientific data.
Think I may test ashwagandha with my stack today, but the huperzine/galantamine are really calling for me, especially with that sweet dosage range.
I think both deserve their own testing after a bit of info, and may even be best combined. Thanks for the info
Qualitative analysis shows similar. No good.
Ashwagandha does not interfere with the effects of the dopamine reward nearly as much, and even provides neuroprotective properties specific to da release, yes bacopa can prevent some toxicity too related to dopamine,there are lot's of reviews on reddit, but in bacopas case it seems like it does much of this by tanking dopamine levels, which ashwagandha only reduces them to a mild, if even noticeable level, while still providing much anti-oxidant, gaba, endorphin, and hopefully ach support.
I do agree bacopa is quite useful, but I would make a formulation based around bacopa rather than add it to an anti-depressant/euphoric mood lifting stimulant stack.