On the subject of the herb, I did dabble with it & alcohol during my adolescence. And I feel both these substances have had long term changes to my brain. I have cut out the herb for a while now, and reduced my drinking significantly.
There is a lot of research saying that marijuana and even alcohol in adolescence can cause permanent cognitive deficits (not seen with those who started in adulthood).
Is it possible for nootropics or even NSI-189 to repair such a brain?